This course is an introduction to working with data for biologists including: data structure, data manipulation, visualization, basic programming, and databases. It is designed to be used as a flipped university course and also for self-guided students. It is taught every fall at the University of Florida by Dr. Ethan White. The full course including video R tutorials, lecture notes and exercises is openly available online so that anyone can learn these important approaches and skills for themselves. Course materials are openly licensed and developed. Anyone is welcome to use the material in their own courses and contributions are always welcome.